Medicine Shortage Information

The following statements have been issued by the State Medical Advisor for the Kentucky Board of Emergency Medical Services.

DuoDote Auto-Injectors

The FDA has further extended the expiration dates of DuoDote to 2 years beyond the manufacturer s expiration date. For more information: .


The Kentucky Board of EMS is currently aware of the drug shortage of D50. The following substitutions may be used.

The typical adult dose is 25 grams of glucose, given as 50 ml. of 50% dextrose solution (500 mg. of dextrose per ml.).

In any situation where D50 would be used, as specified in the Statewide Treatment Protocols, ambulance services may use any of the following acceptable substitutions:

  1. An equal-dose amount of D25. Since this is packaged in 10 ml. syringes, the usual adult dose would be 10 syringes of 10 ml. each of D25, or 100 ml. of D25.
  2. A sterile IV bag containing 250 ml of D10W, delivering 25 grams of glucose.

Printable Statement on Dextrose

Normal Saline Shortage

Click on the documents below for guidance regarding the national shortage of IV Normal Saline, and alternatives.

Additional Information as of March 28, 2014:

Please use the links below to find updated information on the national shortage of IV Normal Saline: